Home / Diagnosis and prognosis / IPSS score

IPSS for MDS

International Prognostic Scoring System (Greenberg et al, 1997)
Risk assessment system to evaluate the prognosis of newly diagnosed MDS patients.

 

Risk group

Score

Median survival

Time to AML transformation

   

(years)

(for 25% in years)
 

Low risk

0

5.7

9.4

INT-1

0.5-1.0

3.5

3.3

INT-2

1.5-2.0

1.2

1.1

High risk

>2.5

0.4

0.2
 

 

Score value
 

Prognostic variable

0

0.5

1

1.5

2

 

BM blasts (%)

<5

5-10

-

11-20

21-30

Karyotype¤

Good

Intermed.

Poor

    

Cytopenias*

0/1

2/3

      
 

 

 
 

 *Good:normal,-Y,del(5q),del(20q). Poor:complex (>3 abnormalities) or chromosome 7 anomalies. Intermediate:other abnormalities.
*Hemoglobin <100 g/l, ANC <1.5 mia/l, platelets <100 mia/l.

Last update: 2011-01-27 |  Go Back |  Print View